{"id":10370,"date":"2015-08-07T08:27:34","date_gmt":"2015-08-07T07:27:34","guid":{"rendered":"http:\/\/catai.net\/blog\/?p=10370"},"modified":"2015-08-07T08:27:34","modified_gmt":"2015-08-07T07:27:34","slug":"diy-paper-based-colorimetric-biochemistry","status":"publish","type":"post","link":"https:\/\/catai.net\/blog\/2015\/08\/diy-paper-based-colorimetric-biochemistry\/","title":{"rendered":"DIY: Paper-based colorimetric biochemistry"},"content":{"rendered":"

In few years blood extraction to obtain biochemical health paramaters will be obsolete and substitute by paper-base colorimetry<\/a>.<\/p>\n

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Teenagers with 3D printers<\/a> are the artifices of analysis that cost just few cents and solve real problems: Heart diseases, \u00a0cancer diagnosis… because colorimetry is linearly related with substrate concentration.<\/p>\n

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  • Intensity derived from RGB histogram analysis provides a quantitative measure of the cholesterol.<\/strong><\/li>\n<\/ul>\n
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    • Color intensity\u00a0varied linearly<\/strong> with cholesterol concentration (100 to 400 mg\/dL) for the dyes TMB, 4-AAP, ADHP<\/li>\n
    • Further linear analysis shows an R2 <\/sup>\u00a0> 0.9 indicating a\u00a0strong correlation between color intensity and cholesterol concentration.<\/li>\n
    • TMB<\/strong>: the green-blue color changed in 30 seconds, suited for mid-range concentrations since double oxidation ocurrs at concentrations >300 mg\/dL producing spots with yellow hues.<\/li>\n
    • 4-AAP<\/strong>: orange color change in 6 min; homogenous color, greater differentiation for low concentrations<\/li>\n
    • ADHP<\/strong>: vibrant magenta color change in 60 seconds, suited for higher concentration<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

      In few years blood extraction to obtain biochemical health paramaters will be obsolete and substitute by paper-base colorimetry.   Teenagers with 3D printers are the artifices of analysis that cost just few cents and solve real problems: Heart diseases, \u00a0cancer diagnosis… because colorimetry is linearly related with substrate concentration.   Intensity derived from RGB histogram […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"give_campaign_id":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_hide_featured_image":false,"_jetpack_featured_image_duplicate_dismissed":0,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[14,11,94,3,40,13,24,66,28],"tags":[175,174],"class_list":["post-10370","post","type-post","status-publish","format-standard","hentry","category-demostradores","category-diagnostico-no-invasivo","category-diy","category-informes","category-innovacion","category-phealth","category-productividad","category-reverse-innovation","category-sanidad","tag-3d-printer","tag-ldl"],"yoast_head":"\nDIY: 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